Supplementary Material

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Abstract

Non-steroidal anti-inflammatory drugs (NSAIDs) can damage the gastrointestinal tract and cause severe complications, such as NSAID-induced enteropathy, which although reported previously, is easily ignored. NSAIDs are commonly used in the elderly owing to higher incidence of comorbidities. NSAIDinduced enteropathy is more important than the previously reported cases. We report a case of an 86-year-old woman who presented with persistent iron deficiency anemia with a positive fecal occult blood test. Initial esophagogastroduodenoscopy and colonoscopy showed no active bleeding. Although proton pump inhibitors were used, the anemia was refractory. Capsule enteroscopy revealed several circular and linear ulcers in the jejunum and ileum. NSAID-induced ulcers were considered. After discontinuing NSAIDs, the anemia improved gradually. In view of this case, we report our experience of typical NSAID-induced enteropathy with a successful clinical outcome.